Identification of a Glutamic Acid Repeat Polymorphism of ALMS1 as a Novel Genetic Risk Marker for Early-Onset Myocardial Infarction by Genome-Wide Linkage Analysis Running title: Ichihara et al.; ALMS1 as a risk marker for myocardial infarction

Sahoko Ichihara, MD, PhD*; Ken Yamamoto, MD, PhD*; Hiroyuki Asano, MD, PhD; Masahiro Nakatochi, PhD; Mayo Sukegawa, PhD; Gaku Ichihara, MD, PhD; Hideo Izawa, MD, PhD; Akihiro Hirashiki, MD, PhD; Fumimaro Takatsu, MD, PhD; Hisashi Umeda, MD, PhD; Mitsunori Iwase, MD, PhD, FACP; Haruo Inagaki, MD, PhD; Haruo Hirayama, MD, PhD; Takahito Sone, MD, PhD; Kazuhiko Nishigaki, MD, PhD; Shinya Minatoguchi, MD, PhD; Myeong-Chan Cho, MD, PhD; Yangsoo Jang, MD, PhD; Hyo-Soo Kim, MD, PhD; Jeong E. Park, MD, PhD; Saeko Tada-Oikawa, PhD; Hidetoshi Kitajima, MD; Tatsuaki Matsubara, MD, PhD; Kenji Sunagawa, MD, PhD; Hiroaki Shimokawa, MD, PhD; Akinori Kimura, MD, PhD; Jong-Young Lee, PhD; Toyoaki Murohara, MD, PhD; Ituro Inoue, MD, PhD; Mitsuhiro Yokota, MD, PhD, FACC